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The stages of fertilization can be divided into of sperm and egg pronuclei and activation of the zygote. .. α-fertilin is capable of fusing model membrane. stages of one and the same spermatozoon - only one penetrates the ovum. Illustration depicting ovulation and fertilization. The sperm entering the ovum using the acrosome head to break down the zona pellucida. Human fertilization is the union of a human egg and sperm, usually occurring in the ampulla of. During the last 15 years, a model for sperm-egg plasma membrane. Fertilization is a complex, multi-step process. This fascinating biological event actually begins with both sperm and eggs undergoing a series of preparatory. After these five steps are accomplished, the haploid sperm and egg nuclei can meet, and the reactions that . (B) In vitro model of species-specific binding.